Title of article
A novel and efficient domino reaction for the one-pot synthesis of spiro-2-aminopyrimidinones
Author/Authors
Ramezanpour، نويسنده , , Sorour and Hashtroudi، نويسنده , , Mehri Seyed and Bijanzadeh، نويسنده , , Hamid Reza and Balalaie، نويسنده , , Saeed، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
3980
To page
3982
Abstract
A novel and efficient protocol is developed for the synthesis of various spiro-2-amino pyrimidinones via the three-component condensation of alkyl cyanoacetates, guanidinium carbonate and N-substituted 4-piperidinones in ethanol at reflux. High yields, neutral conditions, and short reaction times are advantages of this method.
Keywords
One-pot three-component reaction , Domino reaction , Guanidinium carbonate , Spiro-2-aminopyrimidinones , Domino Knoevenagel-cyclocondensation , Neutral conditions
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859553
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