Title of article
Direct perfluoroalkylation of non-activated aromatic C–H bonds of phenols
Author/Authors
Matsugi، نويسنده , , Masato and Hasegawa، نويسنده , , Masakazu and Hasebe، نويسنده , , Shohei and Takai، نويسنده , , Shohei and Suyama، نويسنده , , Ryusuke and Wakita، نويسنده , , Yusuke and Kudo، نويسنده , , Kanako and Imamura، نويسنده , , Hiromi and Hayashi، نويسنده , , Toshiya and Haga، نويسنده , , Seiichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
4189
To page
4191
Abstract
A simple procedure for the perfluoroalkylation of the aromatic ring of phenols under mildly basic conditions is described. Treatment of a variety of phenols with perfluoroalkyl iodide in the presence of the radical initiator V-70L and Cs2CO3 provided the corresponding perfluoroalkylated products in moderate to good yields. Generally, the reaction proceeded smoothly at room temperature to yield regioselectively perfluoroalkylated products.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859659
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