Title of article :
A simple approach to highly functionalized benzo[b]furans from phenols and aryl iodides via aryl propargyl ethers
Author/Authors :
Lingam، نويسنده , , V.S. Prasada Rao and Vinodkumar، نويسنده , , Ramanatham and Mukkanti، نويسنده , , Khagga and Thomas، نويسنده , , Abraham and Gopalan، نويسنده , , Balasubramanian، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
5
From page :
4260
To page :
4264
Abstract :
A variety of mono- and disubstituted phenols are alkylated with propargyl bromide to give phenyl 2-propynyl ethers, which were further coupled with aryl iodides under Sonogashira reaction conditions to give 3-phenoxy-1-aryl-1-propyne derivatives. The latter compounds underwent an initial Claisen rearrangement followed by ring closure to give functionalized benzo[b]furans in moderate to good yields.
Keywords :
Aryl propargyl ethers , Sonogashira coupling , Claisen rearrangement
Journal title :
Tetrahedron Letters
Serial Year :
2008
Journal title :
Tetrahedron Letters
Record number :
1859692
Link To Document :
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