Author/Authors :
Butters، نويسنده , , Michael and Elliott، نويسنده , , Mark C. and Hill-Cousins، نويسنده , , Joseph and Paine، نويسنده , , James S. and Westwood، نويسنده , , Alexander W.J.، نويسنده ,
Abstract :
Improved conditions are reported for the Prins-pinacol rearrangement of cyclohexa-1,4-diene-derived acetals. The use of triflic acid gives particularly clean reaction, resulting in a mixture of regioisomers in an approximately 10:1 ratio. A tethered version of this reaction is also reported, giving a tricyclic compound with the same stereochemistry as the core of the cladiellin diterpenes.
