Title of article
Synthesis of 13C2-benzo[a]pyrene and its 7,8-dihydrodiol and 7,8-dione implicated as carcinogenic metabolites
Author/Authors
Ran، نويسنده , , Chongzhao and Xu، نويسنده , , Daiwang and Dai، نويسنده , , Qing and Penning، نويسنده , , Trevor M. and Blair، نويسنده , , Ian A. and Harvey، نويسنده , , Ronald G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
4531
To page
4533
Abstract
Synthesis of the 13C2-labelled analogues of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene and its active metabolites is described. The method entails Pd-catalyzed Suzuki–Miyaura coupling of a naphthalene boronic acid with 2-bromobenzene-1,3-dialdehyde followed by Wittig reaction of the product with 13CH2PPh3.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859831
Link To Document