Title of article
A novel three-component reaction of anilines, formaldehyde and dimedone: simple synthesis of spirosubstituted piperidines
Author/Authors
Kozlov، نويسنده , , Nikolas G. and Kadutskii، نويسنده , , Aliaksei P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
4560
To page
4562
Abstract
A three-component condensation of anilines with dimedone and formaldehyde leads to the formation of 3,5-dispirosubstituted piperidines. This simple reaction can serve as a convenient source of 3,5-disubstituted piperidines as well as polyfunctional 3-spirofused piperidines.
Keywords
?-diketones , multicomponent reaction , Mannich reaction , piperidines , Azaspiro compounds
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859850
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