Title of article :
A novel three-component reaction of anilines, formaldehyde and dimedone: simple synthesis of spirosubstituted piperidines
Author/Authors :
Kozlov، نويسنده , , Nikolas G. and Kadutskii، نويسنده , , Aliaksei P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A three-component condensation of anilines with dimedone and formaldehyde leads to the formation of 3,5-dispirosubstituted piperidines. This simple reaction can serve as a convenient source of 3,5-disubstituted piperidines as well as polyfunctional 3-spirofused piperidines.
Keywords :
?-diketones , multicomponent reaction , Mannich reaction , piperidines , Azaspiro compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
