• Title of article

    β-Halovinylsilanes in oligoyne synthesis: a fluoride-catalysed unmasking of alkynes from β-fluorovinylsilanes

  • Author/Authors

    Weller، نويسنده , , Michael D. and Kariuki، نويسنده , , Benson M. and Cox، نويسنده , , Liam R.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    5
  • From page
    4596
  • To page
    4600
  • Abstract
    A stereoselective halodestannylation of (E)-β-stannylvinylsilane 6 has been used to access a range of (E)-β-halovinylsilanes. Most notably, the β-fluorovinylsilane 14 was accessed in high yield using the Selectfluor® reagent, and subsequently converted into a masked hexayne 22. Release of the hexayne 25 was achieved by exposing 22 to sub-stoichiometric quantities of fluoride.
  • Keywords
    vinylsilanes , Polyynes , Oligoynes , ?-Elimination , Tin–halogen exchange
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1859863