Title of article :
Lipase-catalyzed preparation of corticosteroid 17α-esters endowed with antiandrogenic activity
Author/Authors :
Ferraboschi، نويسنده , , Patrizia and Mieri، نويسنده , , Maria De and Ragonesi، نويسنده , , Laura، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Several 17α-monoesters of cortexolone and its Δ9-derivative are endowed with antiandrogenic activity. Their synthesis can be accomplished by means of a lipase-catalyzed chemoselective alcoholysis of the corresponding 17α,21-diesters.
Keywords :
Lipase , corticosteroid , antiandrogen , Chemoselective alcoholysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
