Author/Authors :
Cao، نويسنده , , Ke and Jiang، نويسنده , , Yijun and Zhang، نويسنده , , Shu-Yu and Fan، نويسنده , , Chun-An and Tu، نويسنده , , Yongqiang and Pan، نويسنده , , Yuan-Jiang، نويسنده ,
Abstract :
A novel coupling reaction between tetrahydrofuran and olefins is discovered, in which the consecutive C–C and C–Cl bond-forming process takes place via Rh-catalyzed/lewis acid-promoted C–H activation. This reaction could be developed into a straightforward and effective method for rapid access to 2-(2-chloro-2-arylethyl)-tetrahydrofuran compounds.
Keywords :
THF , Coupling reaction , C–H activation , Lewis acid