Title of article
Studies on isocyanides: synthesis of tetrazolyl-isoindolinones via tandem Ugi four-component condensation/intramolecular amidation
Author/Authors
Marcos ، نويسنده , , Carlos F. and Marcaccini، نويسنده , , Stefano and Menchi، نويسنده , , Gloria and Pepino، نويسنده , , Roberto and Torroba، نويسنده , , Tomلs، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
149
To page
152
Abstract
The Ugi four-component condensation between methyl o-formylbenzoates 1, anilines 2a–c, isocyanides 3, and trimethylsilyl azide (4) afforded the expected Ugi adducts 5a–d, which were cyclized to the title compounds 6a–d upon treatment with sodium ethoxide in ethanol. Starting from aralkyl- or alkylamines 2d–g the Ugi adducts underwent a spontaneous cyclization to tetrazolyl-isoindolinones 6e–j.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859913
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