Title of article
A novel hydride-mediated reductive rearrangement of amide: a facile synthesis of pyrimidyl and triazinyl amines
Author/Authors
Chen، نويسنده , , Xiang and Wu، نويسنده , , Jun and Shang، نويسنده , , Zhicai and Chen، نويسنده , , Meifeng and Sun، نويسنده , , Yanping and Lv، نويسنده , , Jing and Lei، نويسنده , , Meikang and Zhang، نويسنده , , Peizhi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
495
To page
499
Abstract
LiAlH4 and NaBH4 were found to mediate the conversion of 2-(pyrimidyl-2-ylsulfanyl)-N-arylbenzamides and 2-(triazinyl-2-ylsulfanyl)-N-arylbenzamides into pyrimidyl and triazinyl amines under notably mild conditions via a novel reductive rearrangement mechanism. These reactions invent a new route to prepare amines, which are a kind of important biologically active compounds and provide the first insight into a novel hydride-promoted reductive rearrangement of amides.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860056
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