Title of article :
Stereoselective synthesis of the C33–C44 fragment of palau’amide
Author/Authors :
Mohapatra، نويسنده , , Debendra K. and Nayak، نويسنده , , Sabita، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
An efficient stereoselective synthesis of the C33–C44 fragment of palau’amide is described using a Sharpless asymmetric epoxidation, a regioselective nucleophilic ring opening of the epoxide, a Grignard reaction and a Luche stereoselective reduction of a keto compound as the key steps.
Keywords :
Palau’amide , Cytotoxic , stereoselective , Sharpless asymmetric epoxidation , Luche’s stereoselective reduction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters