Title of article
A novel reagent combination for the oxidation of highly electron deficient pyridines to N-oxides: trifluoromethanesulfonic anhydride/sodium percarbonate
Author/Authors
Zhu، نويسنده , , Xizhen and Kreutter، نويسنده , , Kevin D. and Hu، نويسنده , , Huaping and Player، نويسنده , , Mark R. and Gaul، نويسنده , , Micheal D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
832
To page
834
Abstract
A novel reagent combination, Tf2O/Na2CO3·1.5H2O2, has been developed for the oxidation of highly electron deficient pyridines to their corresponding N-oxides. The N-oxidation reaction, utilizing the in situ generated peracid, proceeds under mild conditions that allow for a number of functional groups and substitution patterns on the pyridine ring.
Keywords
pyridine , Pyridine N-oxide , Trifluoromethanesulfonic anhydride , sodium percarbonate
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860207
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