Title of article
InBr3-catalyzed stereoselective synthesis of trans-2,6-disubstituted 3,6-dihydro-2H-pyrans
Author/Authors
Yadav، نويسنده , , J.S. and Sunitha، نويسنده , , V. and Reddy، نويسنده , , B.V. Subba and Das، نويسنده , , P.P. and Gyanchander، نويسنده , , E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
855
To page
857
Abstract
A new method for the stereoselective synthesis of trans-2,6-disubstituted 3,6-dihydro-2H-pyrans with a variety of substitution patterns is described, involving Lewis acid induced tandem allylation or cyanation of δ-hydroxy-α,β-unsaturated aldehydes to produce dihydropyrans in good yields and with trans-selectivity. This method is very useful for the synthesis of trans-2,6-disubstituted dihydropyran ring-containing natural products such as laulimalide, scytophycin C and many others.
Keywords
Dihydropyrans , ?-Hydroxy-? , ?-Unsaturated aldehydes , allylation , cyanation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860217
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