Title of article
New functionalised silicas for highly selective cation exchange SPE purification in medicinal chemistry
Author/Authors
Brown، نويسنده , , Jane and Chighine، نويسنده , , Alessandra and Colucci، نويسنده , , Marie A. and Galaffu، نويسنده , , Nicola and Hirst، نويسنده , , Simon C. and Seymour، نويسنده , , Helen M. and Shiers، نويسنده , , Jason J. and Wilkes، نويسنده , , Robin D. and Williams، نويسنده , , Jonathan G. and Wilson، نويسنده , , John R.H. Xie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4968
To page
4971
Abstract
Functionalised silicas 2 and 3 are effective for the cation exchange SPE purification of basic molecules containing acid-sensitive functionalities, the selective separations of mixtures of basic compounds and accelerated reaction work-ups/product isolations.
Keywords
Amine separation , Functionalised silica , Solid phase extraction (SPE) , Immobilised acid , SCX , Purification , cation exchange
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860611
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