Title of article :
1,4-Asymmetric induction in the titanium-mediated aldol reactions of α-benzyloxy methyl ketones
Author/Authors :
Pellicena، نويسنده , , Miquel and Solsona، نويسنده , , Joan G. and Romea، نويسنده , , Pedro and Urpي، نويسنده , , Fèlix، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Good levels of 1,4-anti asymmetric induction are obtained in the TiCl3(i-PrO)-mediated aldol reaction of α-benzyloxy methyl ketones with achiral aldehydes. Such methodology represents a new approach to the substrate-controlled acetate aldol reaction, which can be useful to design more efficient synthesis.
Keywords :
Stereoselective reactions , Acetate aldol reactions , titanium enolates , chiral ketones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
