Title of article
Atropisomerism about a heptafluoroisopropyl to aryl bond in 5-amino-4-heptafluoroisopropyl indazole
Author/Authors
Atouioual، نويسنده , , Bahiya and Hagmann، نويسنده , , Leonhard and Jung، نويسنده , , Pierre M.J. and Lamy، نويسنده , , Emmanuel and Winkler، نويسنده , , Tammo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
2
From page
5403
To page
5404
Abstract
The atropisomerism about a heptafluoroisopropyl to aryl bond in 5-amino-4-heptafluoroisopropyl indazole is reported. The through-space hydrogen fluorine coupling of the indazole H-3 proton with the tertiary F atom is shown to be useful to distinguish the two rotamers. The same atropisomerism is also observed in the analogous indole, benzofuran, and naphthaline derivatives.
Keywords
Atropisomerism , NMR , rotamers , Heptafluoroisopropyl indazole
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860807
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