Title of article
Catalytic enantioselective electrophilic α-hydrazination of β-ketoesters using bifunctional organocatalysts
Author/Authors
Jung، نويسنده , , Sun Hee and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5527
To page
5530
Abstract
The catalytic enantioselective electrophilic α-hydrazination promoted by chiral bifunctional organocatalysts is described. Treatment of β-ketoesters with azodicarboxylates as electrophilic amination reagents under mild reaction conditions afforded the corresponding α-amino β-ketoesters with excellent enantiomeric excesses (93–99% ee).
Keywords
?-Ketoesters , Asymmetric reactions , Bifunctional organocatalysts , Hydrazination
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860859
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