Title of article
Iodine-mediated electrophilic cyclization of 2-alkynylbenzaldoximes leading to the formation of iodoisoquinoline N-oxides
Author/Authors
Huo، نويسنده , , Zhibao and Tomeba، نويسنده , , Hisamitsu and Yamamoto، نويسنده , , Yoshinori، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
5531
To page
5533
Abstract
Reaction of 2-alkynylbenzaldoximes 1 with 5 equiv of iodine in EtOH at room temperature gives the corresponding iodoisoquinoline N-oxides 2 in good to excellent yields. The cyclization proceeds very smoothly and quickly without any additives such as bases under very mild reaction conditions.
Keywords
Iodonium ion , Electrophilic cyclization , iodine , Isoquinoline N-oxide , 2-Alkynylbenzaldoxime , Isoquinoline
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860860
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