Author/Authors :
Pinto، نويسنده , , Angelo C. and Lapis، نويسنده , , Alexandre A. Moreira and da Silva، نويسنده , , Barbara Vasconcellos and Bastos، نويسنده , , Renato S. and Dupont، نويسنده , , Jaïrton and Neto، نويسنده , , Brenno A.D.، نويسنده ,
Abstract :
An efficient method was developed for the preparation of isatin-3-oxime derivatives with Bronsted and/or Lewis acids in imidazolium-based ionic liquids. Isatin-3-oxime bearing the electron donating methoxy group was equally obtained in good yields. The pronounced ionic liquid effect avoids the direct formation of isatin in the acidified media and the reaction leads exclusively to isatin-3-oxime derivatives.
