Author/Authors :
Sabitha، نويسنده , , Gowravaram and Bhikshapathi، نويسنده , , M. and Nayak، نويسنده , , Sambit and Yadav، نويسنده , , J.S. and Ravi، نويسنده , , R. and Kunwar، نويسنده , , A.C.، نويسنده ,
Abstract :
The synthesis of 4-amidotetrahydropyrans has been achieved by a single-step Sakurai–Prins–Ritter reaction sequence in a domino fashion by the reaction of an aldehyde and allyltrimethylsilane in acetonitrile using Bi(OTf)3 as catalyst. The present synthesis is highly efficient and diastereoselective.
Keywords :
tetrahydropyrans , diastereoselectivity , Aldehydes , Bi(OTf)3·4H2O , Sakurai–Prins–Ritter , Allyltrimethylsilane
