Title of article
Iron-catalyzed hydroxylation of β-ketoesters with hydrogen peroxide as oxidant
Author/Authors
Li، نويسنده , , Dongmei and Schrِder، نويسنده , , Kristin and Bitterlich، نويسنده , , Bianca and Tse، نويسنده , , Man Kin and Beller، نويسنده , , Matthias، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5976
To page
5979
Abstract
The hydroxylation of β-ketoesters was studied using simple iron catalysts and 30 wt % hydrogen peroxide as the terminal oxidant. The highest activity and yield were achieved in the presence of iron(III) chloride. Cyclic β-ketoesters could be smoothly hydroxylated in 75–90% yield. For linear β-ketoester and β-ketoamide, the chloro-substituted products were obtained.
Keywords
Iron catalysis , Ketoester , Selective oxidation , Hydrogen peroxide
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861133
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