Author/Authors :
Li، نويسنده , , Dongmei and Schrِder، نويسنده , , Kristin and Bitterlich، نويسنده , , Bianca and Tse، نويسنده , , Man Kin and Beller، نويسنده , , Matthias، نويسنده ,
Abstract :
The hydroxylation of β-ketoesters was studied using simple iron catalysts and 30 wt % hydrogen peroxide as the terminal oxidant. The highest activity and yield were achieved in the presence of iron(III) chloride. Cyclic β-ketoesters could be smoothly hydroxylated in 75–90% yield. For linear β-ketoester and β-ketoamide, the chloro-substituted products were obtained.
Keywords :
Iron catalysis , Ketoester , Selective oxidation , Hydrogen peroxide
