Title of article
Solid-phase synthesis of peptide thioacids through hydrothiolysis of resin-bound peptide thioesters
Author/Authors
Zhang، نويسنده , , Xiaohong and Lu، نويسنده , , Xiao-Wei and Liu، نويسنده , , Chuan-Fa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
6122
To page
6125
Abstract
We report that solid-phase hydrothiolysis is an efficient method to convert resin-bound peptide thioesters to thioacids in aqueous buffer by using a total PEG-based resin. Also demonstrated is the use of the so-prepared peptide thioacids in chemoselective amide bond formation reactions.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861239
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