Author/Authors :
Yeung، نويسنده , , Kap-Sun and Qiu، نويسنده , , Zhilei and Farkas، نويسنده , , Michelle E. and Xue، نويسنده , , Qiufen and Regueiro-Ren، نويسنده , , Alicia and Yang، نويسنده , , Zhong and Bender، نويسنده , , John A. and Good، نويسنده , , Andrew C. and Kadow، نويسنده , , John F.، نويسنده ,
Abstract :
An efficient, one-pot Friedel–Crafts acylation/hydrolysis reaction promoted by the acidic ionic liquid 1-ethyl-3-methylimidazolium chloroaluminate (generated from 1-ethyl-3-methylimidazolium chloride (EmimCl) and aluminum chloride (X(AlCl3), mole fraction X = 0.75) for the formation of 3-glyoxylic acid derivatives of electron-deficient, substituted 4- and 6-azaindoles is described.
Keywords :
Electron-deficient azaindoles , Azaindole-3-glyoxylic acid , Friedel–Crafts acylation , Ionic liquid , imidazolium chloroaluminate
