Title of article :
Kinetic resolution of cyanohydrins via enantioselective acylation catalyzed by lipase PS-30
Author/Authors :
Xu، نويسنده , , Wen-Qing and Geng، نويسنده , , Xiaohong and Chen، نويسنده , , Peiran، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic cyanohydrins has been achieved via enantioselective acylation. The values of kinetic enantiomeric ratio (E) reached up to 314. Substituent effect is also briefly discussed.
Keywords :
kinetic resolution , Enantioselective acylation , Kinetic enantiomeric ratio (E) , Lipase PS-30 , Cyanohydrin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
