Title of article :
Enantioselective organocatalytic Mannich reactions of ferrocenecarbaldehyde
Author/Authors :
Valero، نويسنده , , Guillem and Balaguer، نويسنده , , Andrea-Nekane and Moyano، نويسنده , , Albert and Rios، نويسنده , , Ramon، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
The first examples of highly enantioselective organocatalytic Mannich reactions of ferrocenecarbaldehyde are disclosed. The reaction is catalyzed by simple amino acids and gives access to β-arylamino-β-ferrocenylketones in high yields and with up to 99% ee.
Keywords :
organocatalysis , amino acids , Amines , Ferrocenes , Mannich reaction , Asymmetric catalysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
