Author/Authors :
Matsugi، نويسنده , , Masato and Suganuma، نويسنده , , Misaki and Yoshida، نويسنده , , Shoko and Hasebe، نويسنده , , Shohei and Kunda، نويسنده , , Yoko and Hagihara، نويسنده , , Kotaro and Oka، نويسنده , , Sayaka، نويسنده ,
Abstract :
A convenient methodology for the separation of a fluorous by-product using fluorous chemistry is described. A Mukaiyama coupling reagent bearing a medium fluorous tag, between 40% and 60% fluorine by weight, can be effectively separated from non-fluorous components by increasing the water content of the crude reaction mixture and subsequent filtration. Additional fluorous solid phase extraction is not necessary.
