Author/Authors :
Bernardi، نويسنده , , Anna and Ouellet، نويسنده , , Stéphane G. and Angelaud، نويسنده , , Remy and O’Shea، نويسنده , , Paul D.، نويسنده ,
Abstract :
A two-step, one-pot procedure using methyl chloroformate and lithium borohydride was developed to transform 2-substituted-oxazolines into alcohols. This methodology is compatible with a wide range of substrates including heterocyclic, aromatic, and aliphatic functionalized 2-oxazolines. Best results are obtained with electron-rich and ortho substituted 2-aryl-oxazolines.
