Title of article
Photochemistry of 7-azide-1-ethyl-3-carboxylate-6,8-difluoroquinolone: a novel reagent for photoaffinity labeling
Author/Authors
Leyva، نويسنده , , Elisa and de Loera، نويسنده , , Denisse and Leyva، نويسنده , , Socorro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
6759
To page
6761
Abstract
A novel reagent for photoaffinity labeling, 7-azido-1-ethyl-3-carboxylate-6,8-difluoroquinolone, was obtained by nucleophilic substitution of 1-ethyl-3-carboxylate-6,7,8-trifluoroquinolone. Photochemical reaction of this azide with diethyl amine gave 7-hydrazino-derivative as the major product. This compound was generated by singlet nitrene N–H insertion. In addition, 7-amino-1-ethyl-3-carboxylate-6,8-difluoroquinolone was also obtained.
Keywords
photochemistry , Aryl azide , Singlet nitrene , Photoaffinity labeling , Fluoroquinolone
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861649
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