Title of article
Tandem cross-metathesis/hydrogenation: application to an enantioselective synthesis of pentadecyl 6-hydroxydodecanoate
Author/Authors
Bourcet، نويسنده , , Emmanuel and Virolleaud، نويسنده , , Marie-Alice and Fache، نويسنده , , Fabienne and Piva، نويسنده , , Olivier، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
6816
To page
6818
Abstract
The synthesis of pentadecyl 6-hydroxydodecanoate, a component isolated from the leaves of Artabotrys odoratissimus, has been achieved through a tandem cross-metathesis/hydrogenation sequence. The enantioselective synthesis required first the preparation of a homoallylic alcohol obtained by a free-metal allyl transfer from a camphor derivative to heptanal.
Keywords
metathesis , Hydrogenation , Homoallylic alcohol , Allyl transfer , total synthesis
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861688
Link To Document