Title of article :
A total synthesis of (+)-isolaurepan
Author/Authors :
Tripathi، نويسنده , , Divya Prasanna Kumar، نويسنده , , Pradeep، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A versatile and efficient method for the enantioselective synthesis of 2,7-cis-disubstituted oxepane 1c, (+)-isolaurepan, using oxidative resolution of a secondary alcohol and highly diastereoselective Et3SiH/TMSOTf-promoted reductive cyclization of a hydroxy ketone is described.
Keywords :
Oxidative resolution of secondary alcohols , Cis-selective cyclization , Cyclic ethers , oxepanes , Isolaurepan
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
