Author/Authors :
Caroline Haurena، نويسنده , , Caroline and Sengmany، نويسنده , , Stéphane and Huguen، نويسنده , , Paul and Gall، نويسنده , , Erwan Le and Martens، نويسنده , , Thierry and Troupel، نويسنده , , Michel، نويسنده ,
Abstract :
α-Amino esters have been synthesized using a straightforward three-component reaction among preformed or in situ-generated aromatic or benzylic organozinc reagents, primary or secondary amines and ethyl glyoxylate. The procedure, which is characterized by its simplicity, allows the concise synthesis of phenylglycine and phenylalanine derivatives.