Title of article
An easy and versatile synthesis of ureas from 2-benzylaminopyrimidine
Author/Authors
Gool، نويسنده , , Michiel Van and Bartolomé، نويسنده , , José M. and Macdonald، نويسنده , , Gregor J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
7171
To page
7173
Abstract
A general procedure for the easy and versatile synthesis of ureas from 2-benzylaminopyrimidine is described. This methodology involves the preparation of a highly reactive carbamoyl chloride intermediate that can be further reacted with a high variety of different amines, including highly hindered secondary amines and deactivated anilines with excellent yields. Furthermore, this smooth procedure is compatible with a second functionality on the amine.
Keywords
triphosgene , Synthesis , Ureas , 2-Benzylaminopyrimidine
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861921
Link To Document