Author/Authors :
Klein، نويسنده , , Johannes E.M.N. and M?ller-Bunz، نويسنده , , Helge and Ortin، نويسنده , , Yannick and Evans، نويسنده , , Paul، نويسنده ,
Abstract :
The synthesis of the novel benz[c]azocines, 11a and 11b was achieved following an 8-endo-trig selective intramolecular Heck reaction. Optimisation of this reaction demonstrated that inclusion of both tetra-n-butylammonium sulfate and water was essential for its success. No products from the corresponding 7-exo-trig process were encountered under these conditions.
