Title of article
A facile synthesis of structurally novel 1-aryl-2-arylamino-4-alkyl/phenyl-5-aroyl-1H-imidazoles from amidinothioureas
Author/Authors
Kaila، نويسنده , , Jitendra C. and Baraiya، نويسنده , , Arshi B. and Vasu، نويسنده , , Kamala K. and Sudarsanam، نويسنده , , V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
7220
To page
7222
Abstract
We report here a convenient and efficient two-step synthesis of 1-aryl-2-arylamino-4-alkyl/phenyl-5-aroyl-1H-imidazoles from easily available amidinothioureas. Guanylation of amidinothioureas 1 using mercury(II) chloride as a thiophile yielded amidinoguanidines 2, which reacted with various phenacyl bromides under mild conditions to afford the corresponding diversely functionalized imidazoles 3 in moderate to good yields.
Keywords
Amidinothioureas , Thiophile , Desulfurization , 2-Aminoimidazoles
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861957
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