• Title of article

    Efficient synthesis of 4-vinyl α,β-unsaturated γ-lactams by ring-closing enyne metathesis reactions

  • Author/Authors

    Yang، نويسنده , , Qian and Lai، نويسنده , , Yuanyuan and Xiao، نويسنده , , Wen-Jing and Alper، نويسنده , , Howard، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    3
  • From page
    7334
  • To page
    7336
  • Abstract
    The ring-closing enyne metathesis reaction of alkyl 2-substituted-2-(N-alkynyl acrylamido)esters using the first-generation Grubbs’ catalyst afforded five-membered lactams bearing a 1,3-diene moiety in high isolated yields. In the reaction process, the presence of ethylene gas is essential.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1862040