Title of article
Efficient stereoselective synthesis of benzoxazines via copper-catalyzed three-component coupling reactions
Author/Authors
Xu، نويسنده , , Xiaobing and Liang، نويسنده , , Linfeng and Liu، نويسنده , , Jun and Yang، نويسنده , , Jingyu and Mai، نويسنده , , Lugen and Li، نويسنده , , Yanzhong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
57
To page
59
Abstract
A convenient one-pot synthesis of 1,4-benzoxazines via three-component coupling and subsequent O-cyclization is reported. The present reaction provides an efficient protocol to functionalized 1,4-benzoxazine derivatives in good to high yields from aldehydes, amines and alkynes. Furthermore, the O-annulation process is completely regio- and stereoselective, only the six-membered rings and its Z-isomers were obtained.
Keywords
Three-component couplings , one-pot synthesis , copper catalyst , Benzoxazines
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862153
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