Author/Authors :
Qin، نويسنده , , Lan-Ying and Cole، نويسنده , , Andrew G. and Metzger، نويسنده , , Axel and O’Brien، نويسنده , , Linda and Sun، نويسنده , , Xiling and Wu، نويسنده , , Jin and Xu، نويسنده , , Yan and Xu، نويسنده , , Kai and Zhang، نويسنده , , Ying and Henderson، نويسنده , , Ian، نويسنده ,
Abstract :
A general solid-phase synthesis of 1,2,5-trisubstituted imidazolidin-4-ones is described. The key synthetic transformation incorporates a microwave-assisted condensation of an α-amino amide on solid support with an aldehyde in solution to give the corresponding resin-bound imidazolidin-4-one in a simple one-pot procedure.
