Author/Authors :
Milburn، نويسنده , , Robert R. and McRae، نويسنده , , Ken W.L. Chan، نويسنده , , Johann and Tedrow، نويسنده , , Jason and Larsen، نويسنده , , Robert and Faul، نويسنده , , Margaret، نويسنده ,
Abstract :
The condensation of alkyl phosphonates with aryl esters to give β-ketophosphonates may be carried out at elevated temperatures mediated by LiHMDS under Barbier type conditions. The reaction is scalable, does not require specialized cryogenic equipment, and is general for all aryl and heteroaryl esters examined.
