Author/Authors :
Liang، نويسنده , , Yanke and Raju، نويسنده , , Ravinder and Le، نويسنده , , Tri and Taylor، نويسنده , , Christopher D. and Howell، نويسنده , , Amy R.، نويسنده ,
Abstract :
α-Alkylidene-β-lactams have been prepared in good to excellent yields by olefin cross-metathesis. Electron-poor α-methylene-β-lactams undergo cross-metathesis more rapidly and efficiently than more electron-rich analogs. Significantly, tetrasubstituted alkenes have for the first time been accessed by CM reactions.