Title of article :
Synthesis of 2-methoxy-2-methyl-3-{6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}propanoic acid, a dual PPARα/γ agonist
Author/Authors :
Humphries، نويسنده , , Paul S. and Do، نويسنده , , Quyen-Quyen T. and Wilhite، نويسنده , , David M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Large quantities of an enantiomerically pure novel dual PPARα/γ agonist were required. Three routes were successfully developed to achieve this goal, with the chosen route utilized to deliver 40 g of material.
Keywords :
Pyridine ether , biotransformation , Halopyridine , chiral resolution , chiral auxiliary , Buchwald , PALLADIUM , PPAR
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
