Title of article
Asymmetric synthesis of 2-alkyl-4-hydroxycyclohex-2-en-1-ones by scandium(III) triflate-catalyzed fragmentation of 2-alkyl-3-iodo-1-oxocyclohexan-2,4-carbolactones
Author/Authors
Matsuo، نويسنده , , Jun-ichi and Kawano، نويسنده , , Mizuki and Takeuchi، نويسنده , , Kosuke and Tanaka، نويسنده , , Hiroyuki and Ishibashi، نويسنده , , Hiroyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
1917
To page
1919
Abstract
Fragmentation of (2S,3S,4S)-2-allyl-3-iodo-1-oxocyclohexan-2,4-carbolactone to (4S)-2-allyl-4-hydroxycyclohex-2-en-1-one, a chiral building block of (−)-platensimycin, proceeded efficiently by using scandium(III) triflate in DMF–H2O (1:3) at 100 °C.
Keywords
acid catalysis , fragmentation , chiral building block
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863289
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