Author/Authors :
Latorre، نويسنده , , Antonio and Rodrيguez، نويسنده , , Santiago and Izquierdo-Ridorsa، نويسنده , , Javier and Gonzلlez، نويسنده , , Florenci V.، نويسنده ,
Abstract :
N-Alkyl carbamates of primary amines are easily converted into amides under treatment with Grignard reagents. Consequently, primary amines can be converted into amides in a one-pot reaction through carbamate protection and Grignard addition.