Author/Authors :
Murayama، نويسنده , , Kyoko and Tanabe، نويسنده , , Takamasa and Ishikawa، نويسنده , , Yuichi and Nakamura، نويسنده , , Kensuke and Nishiyama، نويسنده , , Shigeru، نويسنده ,
Abstract :
Gymnastatins F (1) and Q (2) were successfully synthesized using the tandem Michael and aldol reaction of the corresponding spirodienones with hemiacetal functions. Inspection of the optical purities of the substrates suggested that undesired racemization does not proceed during the tandem reaction. Results of theoretical calculations agreed with the ratio of the reaction outcome.
