Author/Authors :
Yoshizumi، نويسنده , , Tomoki and Satoh، نويسنده , , Tetsuya and Hirano، نويسنده , , Koji and Matsuo، نويسنده , , Daisuke and Orita، نويسنده , , Akihiro and Otera، نويسنده , , Junzo and Miura، نويسنده , , Masahiro، نويسنده ,
Abstract :
The direct arylation of 5-aryloxazoles, prepared by the van Leusen reaction, with various aryl iodides is effectively promoted by a system of CuI combined with PPh3 and Na2CO3 as a ligand and a base, respectively, in DMF to produce the corresponding 2,5-diaryloxazoles in good yields.
Keywords :
Oxazole , arylation , aryl iodide , Copper
