Title of article :
Synthesis of prospective disaccharide ligands for Escherichia coli O157 verotoxin
Author/Authors :
Christian Bernlind، نويسنده , , Christian and Homans، نويسنده , , Steven W. and Field، نويسنده , , Robert A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
The synthesis of new potential ligands for Escherichia coli 0157 verotoxin is reported, based on disaccharide fragments of the tetrasaccharide glycan portion of Gb4 glycolipid. Intramolecular aglycone delivery was employed for the high-yielding and stereoselective production of the azidopropyl-tethered α-galactoside building block.
Keywords :
Intramolecular aglycone delivery (IAD) , Gb3 , Verotoxin , Disaccharide , Gb4 , glycosylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
