Author/Authors :
James R. and Oaksmith، نويسنده , , Jennifer Marie and Ganem، نويسنده , , Bruce، نويسنده ,
Abstract :
Guided by a revised mechanism of action for the antitumor agent 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxy-2-cyclohexenone (COTC) recently advanced by our laboratory, an estradiol conjugate of the bioactive COTC analog, COMC, has been synthesized.
