Author/Authors :
Laurenson، نويسنده , , James A.B. and Meiries، نويسنده , , Sebastien and Percy، نويسنده , , Jonathan M. and Roig، نويسنده , , Ricard، نويسنده ,
Abstract :
The isomerisation of readily available (Z)-4-(para-methoxybenzyloxy)-1-chloro-2-butene was achieved under mild conditions to afford the much less accessible E-diastereoisomer. This was an effective substrate in Sharpless asymmetric dihydroxylation (AD) reactions, delivering highly enantiomerically enriched fluorinated butene triol building blocks.
