Author/Authors :
Fujimoto، نويسنده , , Yukari and Konishi، نويسنده , , Yasuko and Kubo، نويسنده , , Osamu and Hasegawa، نويسنده , , Mizuho and Inohara، نويسنده , , Naohiro and Fukase، نويسنده , , Koichi، نويسنده ,
Abstract :
The synthesis of crosslinked peptidoglycan (PGN) fragments from Streptococcus pneumoniae cell wall was achieved. The immunostimulatory activities, including the induction of IL-6 and the stimulation of the intracellular receptor Nod2, were also determined. The crosslinked PGN fragments were not major human Nod2 ligands.
