Author/Authors :
Ko، نويسنده , , Kyungmin and Nakano، نويسنده , , Keiji and Watanabe، نويسنده , , Shigeru and Ichikawa، نويسنده , , Yoshiyasu and Kotsuki، نويسنده , , Hiyoshizo Kotsuki، نويسنده ,
Abstract :
A general and efficient protocol for the Michael addition reactions of β-ketoesters in pure water has been developed. The reactions are successfully catalyzed by newly designed DMAP-related organocatalysts such as 4-(didecylamino)pyridine, and the desired Michael adducts are obtained in good to high yields
Keywords :
?-Ketoesters , aqueous media , DMAP-related organocatalyst , Michael addition reaction
